Elevated Kappa Light Chains In Urine

Thank you for putting things in simple terms and also for the deciphering my myeloma lab results which i printed out.

Elevated kappa light chains in urine.

You have a minimal degree of change this may be wi. Free light chains will normally be present in the blood at low levels with a kappa lambda ratio of approximately 0 26 to 1 65 for individuals with normal kidney function. Leclair provides a thorough scientific breakdown of light chains and the way they work. Light chains molecular weight 22 000 d are polypeptides that are synthesized by plasma cells and form part of immunoglobulins.

The decades old urine test is still used by pathologists and requested by physicians but its use declined when the serum free light chain assay became available about a dozen years ago singh. In this patient power segment host dr. His kappa light chain free serum level is high. There are two types of immunoglobulin light chain produced in humans.

These tests are used as an aid in the diagnosis and monitoring of multiple myeloma and related disorders. Told me my kappa light chain is elevated at 26. Susan leclair discusses what kappa light chains are and answers what an increase in kappa light chain numbers might mean for a patient with myeloma. She told me not to worry and we ll check again in 3 months.

Plasma cells normally produce a slight excess of light chains that are either excreted or catabolized by the kidney and only a minute amount of light chain protein normally appears in the urine. What else should i ask answered by dr. Immunoglobulin light chains that are circulating in serum in a free unbound state are called free light chains flcs measurement of the serum level of flcs became practical as a clinical blood test in recent decades. In the clip dr.

I guess we are going on a journey and i pray he will come out on the other side. Leclair is a patient power host and retired.